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As a society, we are becoming more aware that the decreased activity coupled with increased caloric intake and poor nutrition slowly but inevitably overwhelms our body's ability to maintain a healthy weight.

Being overweight or obese puts you at serious risk of developing many obesity-related diseases. This is bad news. The good news is that reducing your weight significantly reduce the level of risk. For those patients who suffer from these conditions, weight loss can significantly improve or completely eliminate these conditions.

Insulin resistance and diabetes

Obesity causes insulin resistance, decreased biological response to the hormone insulin. This resistance is characterized by circulating insulin, decreased ability to store glucose, and a tendency to store fat in height.

In patients with insulin-dependent diabetes mellitus, serum glucose levels improve within a few days after starting a weight loss program. One study showed that the average fasting blood glucose levels in people with type 2 diabetes decreased from 290 mg / dL to 110 mg / dL within 3 days, given the very low calorie diet. Drugs (oral agents or insulin) can be significantly reduced or eliminated in such cases. Another study reported that after a 23-kg (22% of baseline body weight) in all patients treated with oral insulin and 82% of patients were able to discontinue medication. Similar results were reported weight loss of 9.3 kg. In general, patients with a 15% reduction in total body weight may decide to discontinue oral medications. The smaller decrease in the total body weight can even cure "pre-diabetes", an important cardiovascular risk.

Hypertension

Hypertension increases the weight of overweight individuals. Patients following a very low calorie diet (VLCD's), one study reported a significant reduction in systolic blood pressure 81% of patients, and diastolic pressure 62% of patients (6). Patients who consume a lot of 800 to 1200 kcal diet, which is aligned with weight 10.5 kg showed reduced systolic and diastolic pressure of approximately 20 mm Hg. Approximately three-quarters of the patients' blood pressure returned to normal. Adding exercise regimen for weight loss has been further improvements in blood pressure.

Dyslipidemia

Obesity is often associated with serum triglycerides and total cholesterol. LDL to HDL cholesterol ratio is usually increased, so has a higher risk of heart attacks and strokes. All of these values ??generally improve with weight loss. Often, fasting triglyceride levels, which can be as high as 1000-1500 mg / dL will return to normal levels (sleep apnea

Obesity may be associated with mild to severe respiratory impairment. Increasing obesity is associated with a decrease in blood oxygen saturation. The two main problems arise: obesity hyperventilation syndrome and sleep apnea.

Patients with hypoxemia (low blood oxygen content) and sleep apnea improve rapidly reduce body weight. For every 1 percent decrease weight, sleep apnea patients to reduce their apnea-hypopnea index (the amount they stop breathing at night) 3 percent. In fact, many patients with sleep apnea who sleep with a CPAP machine can stop using their breathing machines at night after weight loss.

Ventilation-perfusion disorder (respiratory vs. circulation mismatch) is common in obese individuals. This disorder can lead to heart failure. These conditions will also improve with weight loss. With significant weight loss, essentially normal lung function can be achieved, and cardiac function can be normalized.

Metabolic Syndrome

Belly fat metabolism and is associated with serious health risks. Metabolic syndrome describes the cardiovascular risk factors, which combine to produce pro-inflammatory and pro-thrombotic (hypercoagulable) state of the cluster. This condition is caused by vascular diseases that cause heart attacks and strokes, and a pro-inflammatory state associated with increased incidence of cancer. It is estimated that more than 50 million Americans currently are at risk, but that less than 5% are diagnosed.

For metabolic syndrome, need 3 out of 5 of the following components: the first increased intra-abdominal fat is determined by the waist circumference greater than 40 cm for men and 35 cm for women second high blood pressure in the third triglycerides fourth low HDL cholesterol fifth diabetes or pre-diabetes. Abdominal obesity is to provide 84% of patients with metabolic syndrome.

In summary, fat space. Belly fat metabolism and dangerous and can cause heart attacks, strokes, cancer, and more. Fortunately, one line of treatment metabolic syndrome are weight reduction and increased physical activity. Waist circumference and abdominal fat decreased significantly with the type of weight loss is usually experienced patients starting line medicine.

Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) affects 5-10% of reproductive age women. He gets along with obesity, type 2 diabetes and ovulatory infertility. As noted above, the weight loss improves diabetes. Weight Loss PCOS patients also can significantly improve their reproductive potential (fertility).

Degenerative joint disease

Low back pain and knee osteoarthritis is more common in obese individuals. Obese women are four times more likely and obese men five times more likely to develop knee osteoarthritis. Fortunately related knee pain and disability, improve or resolve with weight loss. According to Framingham Study, 11 pounds weight loss in women lowered their risk of knee osteoarthritis by 50%. The degree of improvement varies with the structural damage, but relief can often be the average weight.

Social stigmatization and prejudice

In addition, suffer from health risks obese people also suffer from discrimination and loss of competitiveness in our society. Compared with normal-weight counterpart in other levels of power, an obese person is less likely to hire a job and more, which can be paid less if he or she gets the job done. Obese individuals are less likely to be admitted to competitive colleges as they are otherwise identical to normal-weight candidates.

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